Taking to Instagram, the actress who worked with his Miramax production company on seven films including her Oscar nominated role in Pulp Fiction, said she had said she was “angry recently and I have a few reasons.”
Then she posted the #metoo hashtag, the prominent way which women and men from all over the globe that have been sexually harassed have been sharing their stories.
The term gained momentum after actress Alyssa Milano asked victims of sexual assault to come forward in a show of solidarity.
Posting next to an image of her as Beatrix Kiddo, or The Bride in Kill Bill, which was also produced by Miramax, the actress said she felt it “was important to take your time, be fair, be exact”.
She added: “So… Happy Thanksgiving Everyone! (Except you Harvey, and all your wicked conspirators - I’m glad it’s going slowly - you don’t deserve a bullet)”.
Cryptically she signed off with “stay tuned”, suggesting she may speak further on the subject.
The scene depicted in the photograph is one where Thurman's character, Beatrix Kiddo, vows to go on a "rampage of revenge".
Thurman has previously refused to comment on the allegations against Weinstein, who has been accused by more than 90 women of allegations ranging from rape to sexual harassment.
He is being investigated by police in Los Angeles, Beverly Hills, New York and London, but the producer has "unequivocally denied" any allegations of non-consensual sex.
Thurman has yet to offer an official statement on the allegations and when she was asked about them last month she declined to comment.
“I don't have a tidy soundbite for you, because I have learned, I am not a child. And I have learned that when I've spoken in anger, I usually regret the way I express myself," she told Access Hollywood.
"So, I've been waiting to feel less angry, and when I'm ready, I'll say what I have to say."